For example, overexpression of IL-15 mRNA is associated with clinical staging and metastasis in cutaneous T-cell lymphoma (Döbbeling et al., 1998), but we found from the Kaplan-Meier database that IL-15 is more likely to be a protective factor for patients with SKCM. This evidence concerns the gene IL15 and primary cutaneous T-cell non-Hodgkin lymphoma.