STING1 and multiple sclerosis: Notably, it was recently demonstrated that the type I interferon response in microglia induced by GCV was not mediated through STING, attributing to the ability of GCV to reduce neuroinflammation in the cultured microglia and in a mouse model of multiple sclerosis (experimental autoimmune encephalomyelitis, EAE) (Mathur et al., 2017).