Grade 3–4 hematological AEs in chemotherapy and TKIs + chemotherapy group were decreased white blood count (n = 6, 9.8%; n = 5, 10.6%), decreased neutrophil count (n = 5, 8.2%; n = 5, 10.6%), anemia (n = 2, 3.3%; n = 1, 2.1%) and increased ALT/AST (n = 1, 1.6%; n = 1, 2.1%). This evidence concerns the gene GPT and anemia.