In CLP-induced ALI mice, Myricetin activates the Nrf2/HO-1 antioxidant pathway, increases the activity of the antioxidant enzymes SOD and catalase, decreases the expression levels of iNOS and COX-2, and alleviates lung inflammation and oxidative damage (Xu et al., 2021). This evidence concerns the gene HMOX1 and acute respiratory distress syndrome.