DPP4 and acute pancreatitis: It has previously been reported that GLP-1RA may cause acute pancreatitis (Smits and Van Raalte, 2021; AlSaadoun et al., 2022), but two recent network meta-analyses revealed that DPP-4 may increase the risk of acute pancreatitis, while GLP-1RA seems to have no effect (Kanie et al., 2021; Zhuo et al., 2021).