CD274 and non-small cell lung carcinoma: In contrast, a separate retrospective study of previously treated NSCLC patients enrolled onto the phase III OAK trial aimed at comparing anti-PD-L1 therapy versus chemotherapy, showed that in site-specific pair wise comparisons, adrenal gland metastases were associated with greater overall survival in immunotherapy treated patients compared to those with other sites of metastasis including liver and bone (136).