To date, several important immune cell subsets have been found to play a role in the pathogenesis of psoriasis and other autoimmune diseases, including Th1, Th2, Treg, and Th17 cells, and the corresponding cytokines may involve IFN-γ, TNF-α, IL-23, and IL-17 (17). The gene discussed is IFNG; the disease is autoimmune disease.