AITL, PTCL-NOS, and ALCL are prone to loss of CD3 (loss rates are 57.50%, 48.00%, and 40.00%, respectively); ALCL is extremely prone to loss of CD5 (loss rate is 80%); The loss rates of CD7 in AITL, ALCL, ENKTL-N, and T-CUS were 50%, 40%, 36.36% and 33.33, respectively. The gene discussed is CD5; the disease is anaplastic large cell lymphoma.