In addition, immune-histochemistry (Figure 5C) and flow cytometry (Figure 5D) analysis also showed that the Ki-67 expression of the tumor tissues in CD4+ TLEX-CD8086 cells immunized mice was 58.8%, which was significantly lower than that in mice immunized with CD4+ TLEX-null cells (65.6%), LEX-CD8086 (68.9%) and LEX-null (70.6%). Here, MKI67 is linked to neoplasm.