CASP8 and central nervous system cancer: Next, the expression analysis of CASP8 in human astrocyte NHA and 5 immortalized human glioma cell lines (LN-229, U87-MG, A172, U118-MG, and U251-MG) showed that CASP8 expression in astrocytes was lower than that in 5 human glioma cell lines (Figures 10G, H).