MAPT and Alzheimer disease: These genes are involved in plaque deposition, tau protein biosynthesis, neuronal dysfunction, neuroinflammation, autophagy, and other pathological processes related to AD (Chakravarthy et al., 2013; Soto et al., 2016; Muhammad et al., 2019; Adeyemi et al., 2021; Li et al., 2021; Weber and Herskowitz, 2021).