Therefore, GINS2 can regulate the expression of some related immune checkpoint genes in some tumours, to play an essential role in regulating tumour-resistant mode (Figure 5(a)) (∗ represents correlation P < 0.05, ∗∗ represents correlation P < 0.01, and ∗∗∗ represents correlation P < 0.001). The gene discussed is GINS2; the disease is neoplasm.