For instance, the identified TFs, namely, MEF2A, FOS, STAT1, STAT3, JUND, YY1, IRF2, ARID3A, SPIB, TP53, RELA, E2F1, NFKB1, NR3C1, FOXO3, PRDM1, NRF1, and ESR1 are related to various hematological diseases. The gene discussed is NFKB1; the disease is hematologic disorder.