MSH2 and cancer: Furthermore, TUBA1C mRNA had a positive correlation with MMR-related genes (MLH1, MSH6, PMS2, MSH2, and EPCAM) in most cancer types and with TMB in UCS, UCEC, STAD, SKCM, SARC, PRAD, PAAD, LUAD, LGG, KIRC, KICH, COAD, CESC, BRCA, and BLCA.