According to Marei et al. (30), mutations in the TP53 gene disturb the cell cycle, leading cells to lose control over cell proliferation, and resulting in the transfer of damaged DNA to their progeny, which eventually develops into malignant cells; around half of all human breast, colon, lung, liver, prostate, and bladder cancers have p53 mutations. The gene discussed is TP53; the disease is urinary bladder cancer.