HIF1A and cancer: The construction and analysis of ALD-specific networks highlight the therapeutic efficacy of the formulation in managing ALD via its 40 PCs pathway association of the protein targets of ALD-specific 40 PCs revealed that TC mainly regulates pathways associated with cancer and signaling processes like HIF-1, chemokine signaling, PI3K-Akt, etc. The role of these signaling pathways in the progression of ALD is well-known, for example, interactions among cytokines and chemokines play a significant role in disease development (58).