AKT1 and cancer: In this study, we adopted a systematic network pharmacology approach to investigate the hepatoprotective effects of TC in ALD and it indicates that the hepatoprotective effects of TC are manifested by the multitude of mechanisms involving regulating cancer and signaling processes like AGE-RAGE signaling, HIF-1 signaling, NF-Kappa B signaling, PI3K/Akt signaling responsible for anti-inflammatory, anti-oxidant and anti-apoptotic role.