With respect to the evaluation of specified follow-up durational data from the included articles, it was apparent that 2 studies [38, 39], which stated their patient follow-up durations as being for over a period of less than 10 years, concurred to the significant impact that FN species within oral biofilm has on the promotion of female-specific BC pathogenesis (RR = 1.18, 95% CI = 1.15–1.29) (Table 2). The gene discussed is FN1; the disease is breast cancer.