Box plot also shows that macrophages M1 and M2, B cell memory, T cell CD4 naive, NK cell activated, dendritic cell resting, and mast cell resting were significantly increased in DKD samples, while B cell naive, T cell CD4 memory resting, and mast cell activated were significantly decreased (p < 0.05) (Figure 6(b)). This evidence concerns the gene CD4 and diabetic kidney disease.