CCL22 and Pruritus: The concentrations of microbicidal peptide human neutrophil α-defensins, dermcidin and Th2-related chemokines CCL17, macrophage-derived chemokine (MDC)/CCL22, and cutaneous T-cell-attracting chemokine (CTACK)/CCL27 in patients with AD were significantly increased, among them CCL27 and CCL22 were positively correlated with SCORAD, meanwhile, CTACK was positively correlated with pruritus in patients with AD (57).