AD-preferred Th2 skewing, TARC, and CTACK levels were significantly correlated with the severity of AD in both skin lesions and non-skin lesions in children with AD using the tape stripping method and so did IL-8, IL-18, and Vascular Endothelial Growth Factor (VEGF), among these three cytokines, IL-8 showed the highest correlation with the disease severity in patients with AD (61–63). The gene discussed is VEGFA; the disease is Alzheimer disease.