The role of chemokine ligand 20 and Chemokine receptor type 6 (CCR6), its receptor is notable in the pathogenesis of colorectal cancer, enlisting the body's defense cells, and has a contradictory role in regulating inflammation and immune tolerance [16]. An animal study conducted in mice has also shown overexpression of chemokine ligand 20, and its receptor chemokine receptor type 6 is incredibly significant in the pathogenesis of colorectal cancer [21]. Here, CCR6 is linked to colorectal cancer.