A screening battery of blood tests that may elicit a cause include full blood count, urea and electrolytes (U&Es), liver function tests (LFTs); thyroid function tests (TFTs); angiotensin-converting enzyme (ACE); anti-neutrophil cytoplasmic antibodies (ANCA); zinc, iron, and magnesium levels; venereal disease research laboratory (VDRL); haemoglobin A1C (HbA1c); 9 am cortisol levels; and vitamin B12 and folate levels to screen for medical/metabolic causes (Table 1) [77]. The gene discussed is ACE; the disease is glycogen storage disease VI.