Caspase-9/3, Bax, ASK1, JNK, and Cty-C mRNA expression increased in the PCOS group compared to the control group (p < 0.05), whereas the mRNA level expression of these indices decreased after treatment with the CFDT decoction and metformin (p < 0.05). The gene discussed is CASP9; the disease is polycystic ovary syndrome.