From the up-regulated gene cluster 7, we identified OMD, JAK2, MMP3 and CSFI while from up-regulated gene cluster 17 we identified CLIP and SOD2. From the down-regulated gene cluster 12, we identified SOX9, APCDD1L, NCEH1 and LRP8 while from down-regulated gene cluster 15 we identified PDK1. The selected genes identified in the data set and their function in osteogenic differentiation are listed in Table 1. The gene discussed is SOD2; the disease is occult macular dystrophy.