A cox model was constructed based TCGA-PAAD dataset with the following formula: 0.172 * ADAMTS12 + (-0.0870) * CHST11 + 0.127 * DCBLD2 + -0.202 * FN1 + 0.0581 * FRMD6 + 0.266 * KRT17 + (-0.089) * LOXL2 + (-0.196) * MMP14 + (-0.0935) * NRP2 + 0.238 * PPFIBP1 + 0.287 * TGFBI + 0.220 * VCL. The gene discussed is LOXL2; the disease is pancreatic adenocarcinoma.