Finally, AVEN and DNAJB1 (19, 20), which have DNA damage and tumor formation roles in tumors were selected to verify their protein expression levels in BGC-823 control and METTL3 overexpression cell lines, and the results showed that the AVEN and DNAJB1 level were significantly upregulated by METTL3 expression (Figure 6H). Here, AVEN is linked to neoplasm.