KLK3 and posterior cortical atrophy: Regarding the diagnosis of PCa, the AUC, sensitivity, and specificity were 0.915 (95% CI: 0.894–0.933), 85.71%, and 87.12%, respectively, for the combined PI-RADS score with PSAD, which was obviously higher than age, PSA, PV, and PSAD (P < 0.001), but no statistical difference was observed compared with the PI-RADS score (P = 0.148) (Table 2).