Furthermore, mutations in the Parkin (PARK2) gene, encoding E3 ubiquitin protein ligase parkin, PINK1 (PARK6), encoding PTEN-induced putative kinase 1, and DJ-1 (PARK7), encoding the deglycase protein DJ-1, are involved in the autosomal recessive forms of PD [55]. This evidence concerns the gene PARK7 and Parkinson disease.