TNF and neoplasm: Hirokazu Ogino et al. pretreated DCs with poly‐ICLC and found that in addition to upregulating cytokines such as IFN‐γ, TNF‐α, and IL‐10,95 the migration of effector memory CD8+ T cells in the TME may be mediated through the CXCL10/CXCR3 axis,96 which showed the activating DCs can effectively improve the migration of other immune cells and improve the tumor microenvironment by regionalization factors.