Hirokazu Ogino et al. pretreated DCs with poly‐ICLC and found that in addition to upregulating cytokines such as IFN‐γ, TNF‐α, and IL‐10,95 the migration of effector memory CD8+ T cells in the TME may be mediated through the CXCL10/CXCR3 axis,96 which showed the activating DCs can effectively improve the migration of other immune cells and improve the tumor microenvironment by regionalization factors. This evidence concerns the gene CD8A and neoplasm.