PPIB and acute respiratory distress syndrome: Mohammed et al. demonstrated that Δ9-THC could lead to a 100% survival rate, decreased lung inflammation, and the suppression of cytokine storm in a mouse model of ARDS induced by staphylococcal enterotoxin B, suggesting Δ9-THC could be used to treat ARDS associated with COVID-19.445 Pitakbut et al. reported that Δ9-THC acts as an inhibitor against both Mpro and ACE2 with IC50 values of 16.23 ± 1.71 μM and 11.47 ± 3.60 μM, respectively.446