At the same time, we evaluated the proportion of TIICs in HCC based on the differential expression of CD97 using CIBERSORT analysis and found significant differences in the proportions of eight types of immune cells: CD8+ T cells, naive CD4+ T cells, regulatory T cells, resting NK cells, monocytes, M0 macrophages, activated dendritic cells, and resting mast cells. This evidence concerns the gene CD4 and hepatocellular carcinoma.