We indeed measured high levels of IL-6 (1.17 ± 0.16 ng/ml) and IL-8 (2.98 ± 0.63 ng/ml) in the supernatant of 24 h 8505C culture (5 × 103 cells in 200 μl), supporting them as indicators of tumor progression and remission (Supplementary Fig. 1). Here, IL6 is linked to neoplasm.