For example, some target genes of the common IC-lncRNA RP11-445H22 have been used as anticancer drugs targets, such as CTLA4 as a target of radotinib in cutaneous melanoma, EGFR and ERBB2 as targets of afatinib in metastatic non-small-cell-lung-cancer. Here, CTLA4 is linked to non-small cell lung carcinoma.