CDX2 and colorectal cancer: At the same time, CDX-2 (+) and SATB2 (+) was discussed as combination marker to discriminate colorectal carcinoma from other primary carcinoma [9, 10], and 19% of gastrointestinal adenocarcinoma with CK7 (+) /CDX-2 (+) /SATB2 (+) showed primary colorectal cancer [11].