There was no significant correlation between clinical characteristics and CD3+, CD4+ and CD8+ T-cell infiltration in ccRCC tissue, except for Vimentin (PCD3 = 0.035, χ2 = 4.432), (PCD4 = 0.020, χ2 = 5.449), (PCD8 = 0.027, χ2 = 4.916) and ISUP grade (PCD4 = 0.023, χ2 = 9.545). The gene discussed is CD4; the disease is nonpapillary renal cell carcinoma.