LGALS3BP and Hepatic fibrosis: Non-invasive tests for diagnosing liver fibrosis may reduce the number for unnecessary liver biopsies and identify patients at higher risk of CVD. As proof, in a population-based cohort study of 3512 individuals, Tamaki et al. [68] examined the associations between non-invasive biomarkers of liver fibrosis [including Fibrosis-4 (FIB-4) index, non-alcoholic fatty liver disease fibrosis score (NFS), and Wisteria floribunda agglutinin-positive Mac-2 binding protein (WFA+-M2BP)] and risk of CVD events.