After adjusting for multiple variables (sex, age, BMI, hypertension, diabetes, urea, Crea, Ua, eGRR, hs-CRP, TC, and Tg), in binary logistic regression, with the increase in the MHR level, the probability of occurrence of carotid plaque increased by approximately 2-fold, and in the multiple regression model, the probability of multiple occurrences of carotid plaques increased by approximately 3-fold. The gene discussed is CRP; the disease is Hypertension.