VIM and hepatocellular carcinoma: the expression of N-cadherin (N-ca), Vimentin (Vim), and Snail was also increased obviously, whereas the expression of E-cadherin (E-ca) displayed an opposite trend both in HepG2 and MHCC97H cells, implying that platelet stimulation could induce epithelial-mesenchymal transition (EMT) in HCC cells (Fig. 11B).