CD44 and neoplasm: Emerging evidence has mentioned that the cell adhesion molecule CD44, which was well demonstrated to regulate cell proliferation, adhesion, and migration, plays an important role in angiogenesis (Chen et al. 2020; Jaskuła et al. 2021; Savani et al. 2001), both in the tumor angiogenesis (Cao et al. 2006; Ludwig et al. 2019) and ischemia angiogenesis (Chen et al. 2020).