INS and diabetes mellitus: Finally, 72 patients (baseline age 63.8 ± 9.5 years, HbA1c 6.4 ± 0.7% [46 ± 8 mmol/mol], BMI 33.01 ± 6.47 kg/m2, body weight 92.92 ± 18.83 kg, TDD 43.21 ± 10.80 IU/day, insulin requirement 0.48 ± 0.13 IU/kg, duration of diabetes 9.7 ± 7.5 years; mean ± SD) completed the 12‐month trial (Table 1).