Twelve protein markers (cytokines: IL-15 and SCF; chemokines: fractalkine and MCP-3; growth factors: Flt-3 L, HGF, PDGF-AA, and VEGF; an apoptosis-related protein, sFasL; and immune checkpoint proteins: HVEM, TIM-3, and TLR2) significantly correlated with both tumor size and depth of myometrial invasion. This evidence concerns the gene CX3CL1 and neoplasm.