KMT2A and acute lymphoblastic leukemia: It has been reported in the literature [7, 20] that WBC and MLL-r positive at disease onset were important factors affecting the prognosis of children with ALL, and the results of the multivariate analysis of 124 children with ALL in our study also showed that WBC ≥50 × 109/L was an independent risk factor affecting the outcome of patients with ALL, which was consistent with the literature.