Among patients with ALL, the 10-year predicted EFS for MLL-AF4 positive, MLL-PTD positive, MLL-ENL positive, other MLL gene partner positive and MLL-r negative children were 46.67 ± 28.61%, 85.71 ± 22.37%, 75 ± 32.41%, 75 ± 32.41% and 77.33 ± 10.81%, respectively (P = 0.048) (Fig. 4A). The gene discussed is AFF1; the disease is acute lymphoblastic leukemia.