PRPF31 and retinitis pigmentosa 1: By segregation analysis in unaffected relatives (parents), we confirmed the incomplete penetrance of the autosomal dominant RP phenotype in family members of three apparently sporadic cases carrying bona-fide pathogenic variants in PRPF31 (c.73G>T, p.Glu25*; c.549delG, p.Glu183Aspfs*15; c.615C>A, p.Tyr205*).