Being inspired by the idea that inflammatory immune cells could be recruited to promote tumor growth, Hyeon et al. developed a click reaction-assisted immune cell targeting (CRAIT) strategy to deliver nanomedicines to the inside of tumors.133 TCO was linked to CD11b antibody (anti-CD11b-TCO) and Tz was conjugated to DOX-loaded mesoporous silica nanoparticles (MSNs-Tz). This evidence concerns the gene ITGAM and neoplasm.