KRT19 and neoplasm: IHC analysis of the TDO using colorectal markers showed that repopulated 3D-dECMs retain the main characteristics and the morphology of their tumor of origin (Figure 5B; Supplementary Figure S4D and F), expressing the colorectal markers in almost the same percentage of cells as their tissue of origin (Figure 5B and C; Supplementary Figure S4H and I), except for CK20 and CK19 more expressed in the ex vivo model, probably because decellularized matrices stimulate their expression.