Decreased lipoprotein lipase (LPL) activity in SCD has been reported in previous studies(Kim, Jia, Buckett, Liu, Lee, Wessling-Resnick 2013; Vendrame, Olops, Saad, Costa, Fertrin 2019), which may explain relatively increased triglycerides in smaller subclasses of VLDL and IDL, while decreased levels of cholesterol in smaller VLDL suggest decreased lipoprotein levels and reduced rate of lipoprotein metabolism. Here, LPL is linked to Schnyder corneal dystrophy.