The first 17 amino acids of Hs HTT are deleted (Fig. 1B), causing increased nuclear localization of HTT protein and acceleration of HD pathology.30 For controls, we used wild-type mice (carrying Mm Htt) (Fig. 1C) and B31-ΔN17 mice carrying Mm Htt and the same Hs HTT transgene as B97-ΔN17 mice, but with 31 repeats instead of 9730 (Fig. 1D). The gene discussed is HTT; the disease is Huntington disease.