Here, we report that, in B16-F10 melanoma cells, ACB1801 upregulates the expression of proteins involved in the MHC-I peptide-loading complex, such as transporter associated with antigen processing proteins 1 and 2 (TAP1 and TAP1), Tapasin and low-molecular-weight proteins 2 (Lmp2). The gene discussed is TAP1; the disease is melanoma.