AKT1 and type 1 diabetes mellitus: Our results showed that hypermethylated transcripts were enriched in the JAK-STAT signaling pathway and MAPK signaling pathway, while hypomethylated transcripts were enriched in the PI3K-Akt signaling pathway and MAPK signaling pathway, indicating the potential roles of m6A in the pathogenesis of T1DM (Figures 5A, B, 6A, B).