The association between serum Klotho concentration and all-cause and cardiovascular mortality was consistent in subgroups according to sex, age, smoking status, DBP (≥90 vs. <90 mmHg), SBP (≥140 vs. <140 mmHg), BMI (≥25 vs. <25 kg/m2), eGFR (≥60 vs. <60 mL/min/1.73 m2), and presence or absence of diabetes and CVD (Figure 4; P for interaction >0.05). Here, KL is linked to diabetes mellitus.