PCED1B and hepatocellular carcinoma: Fan et al. (Fan et al., 2021) found that PCED1B-AS1 overexpression in hepatocellular carcinoma cells has been shown to impair the activity of co-cultured T cells and cause immunosuppression; In addition, Li et al. (Li et al., 2019) demonstrated that by directly binding to miR155, PCED1B-AS1 controls macrophage apoptosis and autophagy.