Knockout of lncRNALUCA T1 can inhibit myocardial injury in sepsis induced by LPS; An et al. (An et al., 2021) believe that LncRNA ZFAS1, as the ceRNA of miR-138-5p, up-regulates the expression of SESN2, thus improving cardiomyocyte scorch death induced by sepsis. The gene discussed is SESN2; the disease is Sepsis.